Corresponding Author: Rouhollah Haghshenas, Assistant professor of exercise physiology, Semnan University, Semnan, Iran.

Co-Authors: Mohsen Ebrahimi;
Assistant professor of Exercise Physiology, Faculty of Human Sciences, Semnan University, Semnan, Iran.
Samaneh Nazemian
Master science of Exercise Physiology, Faculty of Human Sciences, Semnan University, Semnan, Iran

Article in press:

The prevalence of overweight and obesity have increased dramatically worldwide and together they constitute a major risk factor for coronary heart disease. The aim of this study was to assess the effect of acute high intensity aerobic training on ANP and Endothelin-1 in inactive obese women. In order to nineteen obese women mean age± SD: 27.94± 3.30, mean weight ±SD: 88.13 ±7.28, mean height ±SD: 163.00± 4.91, mean BMI ±SD: 32.96± 3.13 selected and were randomly allocated to experimental and control groups. Experimental group performed a session acute aerobic exercise on Ergometer at intensity 25w that increased every two minutes 25w to workload and performed to exhaustion every subject. Samples blood was taken after 12 hours fasting, before and after of program training. For analyzed of biochemical variables used ELISA method and for analyses data used ANOVA. The results of this study showed that acute aerobic training causes significant increase in the level of plasma ANP in obese women (p=0. 006). But no significant differences observe in plasma level of Endothelin-1. Finally, on the results of this study, one session acute aerobic training causes significant increase in level ANP and may represent an optimal therapeutic agent in cardiovascular diseases. Also the NP pathway may offer a novel therapeutic avenue for the management of obesity and type 2 diabetes.

Journal name: International Journal of Applied Exercise Physiology

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Asian Exercise & Sport Science Association


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